BHRT FOR MEN

Testosterone can be compounded in different strengths and dosage forms to meet your patient’s individual needs.  We can also compound with DHEA, Anastrozole, and Chrysin as well as other combinations for men.  Hormones can be compounded as oral tablets, sublingual tablets, or creams, as well as other dosage forms.  We can combine multiple hormones in one dosage form.  Belmar can provide you with prescribing templates to ease the writing of compounded hormone prescriptions.
 
Testosterone USP is bio-identical testosterone that has been approved by the United States Pharmacopoeia and is available as a bulk powder.  The testosterone comes from natural sources and then is purified by a major pharmaceutical company into the bio-identical form.  The term "Bio-Identical” means that the testosterone has the same molecular structure as the testosterone made in the human body and is chemically and functionally the same.  Testosterone is a scheduled III controlled substance.
 
 
 

Research

Clinical Practice 
 
Loria K. Polycythemia risk evaluated in patients on TRT pellets. Urology Times website. http://urologytimes.modernmedicine.com/urology-times/news/polycythemia-risk-evaluated-patients-trt-pellets?page=0,1. December 06, 2016. Accessed January 24, 2019.

Schwartz E, Holtorf K, Brownstein D. The Truth About Hormone TherapyThe Wall Street Journal, March 06, 2016:A17.
 
Morley J. The benefits and risks of testosterone replacement therapy: a review.  Therapeutics and Clinical Risk Management, 2009; 5:427-448.
 
 
 Metabolic Syndrome

 
Rubinow KB. Estrogens and Body Weight Regulation in MenAdv Exp Med Biol, 2017; 1043:285-313.
 
Kelly D, Jones T. Testosterone: a metabolic hormone in health and disease. Journal of Endocrinology, 2013; 217(3):R25-R45.
 
Muraleedharan V, Hugh Jones T. Testosterone and the metabolic syndrome.  Ther Adv Endocrinol Metab, 2013; 1(5):207–223.

Diabetes 

Haider A, Haider K, Saad F, Hanefeld M. Remission of type 2 diabetes and pleiotropic effects of long-term testosterone treatment for "late-onset" hypogonadism: A case reportSAGE Open Med Case Rep, 2019; 7:2050313X18823454.


 

 
 

Muraleedharan V, Marsh H, Kapoor D, Channer K, Jones T. Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 2013; 169(6):725-733. 

 
Mortality

 
Comhaire F. Hormone replacement therapy and longevity. Andrologia, 2015; 48(1): 65-68.

Shores M, Smith N, Forsberg C, Anawalt B, Matsumoto A.  Testosterone Treatment and Mortality in Men with Low Testosterone LevelsThe Journal of Clinical Endocrinology & Metabolism, 2012; 97(6):2050-2058. 
 
Laughlin G, Barrett-Connor E, Bergstrom J. Low Serum Testosterone and Mortality in Older Men. The Journal of Clinical Endocrinology & Metabolism, 2008; 93(1):68-75.
 
 
 
Cancer
 
Roddam A, Allen N, Appleby P, Key T. Endogenous Sex Hormones and Prostate Cancer: A Collaborative Analysis of 18 Prospective Studies. Journal of the National Cancer Institute, 2008; 100(3):170-183.
 
 

DHEA
 
Villareal D, Holloszy J.  Effect of DHEA on Abdominal Fat and Insulin Action in Elderly Women and MenJAMA, 2004; 292(18):2243.
 
Oberbeck R, Dahlweid M, Koch R, et al. Dehydroepiandrosterone decreases mortality rate and improves cellular immune function during polymicrobial sepsis. Critical Care Medicine, 2001; 29(2):380-384.
 
Wolkowitz O, Reus V, Keebler A, Nelson N, Friedland M. Double-Blind Treatment of Major Depression with Dehydroepiandrosterone. The American Journal of Psychiatry, 1999; 156(4):646-649. 
 
 
Anti-Aging
 
 
Comhaire F.  Hormone replacement therapy and longevityAndrologia, 2016; 48(1):65-8.
 
Frederiksen L, Højlund K, Hougaard DM, Brixen K, Andersen M.  Testosterone therapy increased muscle mass and lipid oxidation in aging menAge (Dordr), 2012; 34(1):145-56.
 

Sexual Function
 
 
Corona G, Rastrelli G, Morgentaler A, et al. Meta-analysis of Results of Testosterone Therapy on Sexual Function Based on International Index of Erectile Function ScoresEur Urol, 2017; 72(6):1000-1011.
 
 

Cardiovascular
 
 

Neuromuscular
 
Recovery Otzel DM, Lee J, Ye F, Borst SE, Yarrow JF.  Activity-Based Physical Rehabilitation with Adjuvant Testosterone to Promote Neuromuscular Recovery after Spinal Cord Injury Int J Mol Sci, 2018;19(6).
 
 
Hypogonadism
 
 
Sumii K, Miyake H, Enatsu N, Matsushita K, Fujisawa M.  Prospective assessment of health-related quality of life in men with late-onset hypogonadism who received testosterone replacement therapyAndrologia, 2016; 48(2):198-202.
 
 
 
Alzheimer’s Disease
 
Pike CJ, Carroll JC, Rosario ER, Barron AM.  Protective actions of sex steroid hormones in Alzheimer's diseaseFront Neuroendocrinol, 2009; 30(2):239-58.
 
Inflammation
 
Traish A, Bolanos J, Nair S, Saad F , Morgentaler A.  Do Androgens Modulate the Pathophysiological Pathways of Inflammation? Appraising the Contemporary EvidenceJ Clin Med, 2018; 7(12). pii: E549.
 
 
 
 
 
 

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